黄俊教授

文章出处: 作者: 发布时间: 2015-02-13 访问次数: 599

 

黄俊, 浙江大学生命科学研究院教授、博士生导师、国家杰出青年科学基金获得者、中组部首批“青年拔尖人才计划”

 

教育背景:

1997-2001,南开大学生命科学学院微生物学专业,学士

2001-2006,北京大学生命科学学院细胞生物学专业,博士

 

工作经历:

2006-2009Yale University,博士后

2009-2010M.D. Anderson Cancer Center,博士后

2010.1-今,浙江大学生命科学研究院教授、博士生导师

 

代表性论文: (*通讯作者)

1. Dong, S., Han, J., Chen, H., Liu, T., Huen, M.S., Yang, Y., Guo, C., and Huang, J.* (2014). The Human SRCAP Chromatin Remodeling Complex Promotes DNA-End Resection. Curr Biol. 24, 2097-2110.

2. Han, J., Liu, T., Huen, M.S., Hu, L., Chen, Z., and Huang, J.* (2014). SIVA1 directs the E3 ubiquitin ligase RAD18 for PCNA monoubiquitination. J Cell Biol. 205, 811-827.

3. Liu, T.*, and Huang, J.* (2014). Quality control of homologous recombination.

Cell Mol Life Sci. 71, 3779-3797. (Invited reivew)

4. Ren, W., Chen, H., Sun, Q., Tang, X., Lim, S.C., Huang, J.*, and Song, H.* (2014). Structural basis of SOSS1 complex assembly and recognition of ssDNA. Cell Rep. 6, 982-991.

5. Wan, L., and Huang, J.* (2014). The PSO4 protein complex associates with replication protein A (RPA) and modulates the activation of ataxia telangiectasia-mutated and Rad3-related (ATR). J Biol Chem. 289, 6619-6626.

6. Ping, X.L., Sun, B.F., Wang, L., Xiao, W., Yang, X., Wang, W.J., Adhikari, S., Shi, Y., Lv, Y., Chen, Y.S., Zhao, X., Li, A., Yang, Y., Dahal, U., Lou, X.M., Liu, X., Huang, J., Yuan, W.P., Zhu, X.F., Cheng, T., Zhao, Y.L., Wang, X., Rendtlew Danielsen J.M., Liu, F., Yang, Y.G. (2014). Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase. Cell Res. 24, 177-189.

7. Wang, W., Li, X., Huang, J., Feng, L., Dolinta, K.G., and Chen, J. (2014). Defining the protein-protein interaction network of the human hippo pathway. Mol Cell Proteomics 13, 119-131.

8. Wan, L., Lou, J., Xia, Y., Su, B., Liu, T., Cui, J., Sun, Y., Lou, H.*, and Huang, J.* (2013). hPrimpol1/CCDC111 is a human DNA primase-polymerase required for the maintenance of genome integrity. EMBO Rep. 14, 1104-1112.

9. Wan, L., Han, J., Liu, T., Dong, S., Xie, F., Chen, H., and Huang, J.* (2013). Scaffolding protein SPIDR/KIAA0146 connects the Bloom syndrome helicase with homologous recombination repair. Proc Natl Acad Sci U S A 110, 10646-10651.

10. Wang, W., Huang, J., Wang, X., Yuan, J., Li, X., Feng, L., Park, J.I., and Chen, J. (2012). PTPN14 is required for the density-dependent control of YAP1. Genes Dev. 26, 1959-1971.

11. Liu, T., Chen, H., Kim, H., Huen, M.S., Chen, J.*, and Huang, J.* (2012). RAD18-BRCTx interaction is required for efficient repair of UV-induced DNA damage. DNA Repair 11, 131-138.

12. Sy, S.M., Jiang, J., Dong, S.S., Lok, G.T., Wu, J., Cai, H., Yeung, E.S., Huang, J., Chen, J., Deng, Y., and Huen, M.S (2011). Critical roles of ring finger protein RNF8 in replication stress responses. J Biol Chem. 286, 22355-22361.

13. Liu, T., Wan, L., Wu, Y., Chen, J.*, and Huang, J.* (2011). hSWS1.SWSAP1 is an evolutionarily conserved complex required for efficient homologous recombination repair. J Biol Chem. 286, 41758-41766.

14. Wang, W., Huang, J.*, and Chen, J.* (2011). Angiomotin-like proteins associate with and negatively regulate YAP1. J Biol Chem. 286, 4364-4370.

15. Su, X., and Huang, J.* (2011). The Fanconi anemia pathway and DNA interstrand cross-link repair. Protein Cell 2, 704-711. (Invited reivew)

16. Liu, T., Huang, J.*, and Chen, J.* (2010). RAD18 lives a double life: Its implication in DNA double-strand break repair. DNA Repair 9, 1241-1248.

17. Liu, T., Ghosal, G., Yuan, J., Chen, J.*, and Huang, J.* (2010). FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair. Science 329, 693-696.