周丛照教授

文章出处: 作者: 发布时间: 2015-02-13 访问次数: 323

Name:   Cong-Zhao ZHOU (周丛照)  

Born:     November 1, 1968, Hubei, P. R. China

Address:       School of Life Sciences, University of Science and Technology of China, 230027 Hefei, P. R. China      

Tel: 86-551-3600406, 3600407

Fax: 86-551-3600406

e-mail: zcz@ustc.edu.cn

Homepage: http://czlab.ustc.edu.cn

Education:

Feb. 1997 - May 2000 Department of Biology, University of Science and Technology of China

                                    (USTC) and Université Paris-Sud, Ph.D student

Sept. 1993 - June 1995 Department of Biology, USTC, Graduate Student

Sept. 1987 - July 1992 Department of Biology, USTC, Undergraduate Student


PROFESSIONAL EXPERIENCE:

May 2014 -                   Dean, Undergraduate Education Office, USTC        

Apr. 2009- May 2014           Deputy Dean, School of Life Sciences, USTC

Jan. 2004 -                   Professor of Biochemistry and Molecular Biology, USTC

Feb. 2001 - Dec. 2003 Laboratoire de Génomique Structurale, Bat 430, CNRS & Université

                          Paris-Sud, Postdoc

Sept 2000 - Jan. 2001 Institut de Génétique et Microbiologie, Université Paris-Sud et CNRS,

                          91405 Orsay Cedex, France, Postdoc

Jan. 1999 - Feb. 2000 Institut de Génétique et Microbiologie, Université Paris-Sud et CNRS,

                         91405 Orsay Cedex, France, joint Ph.D student

Jan. 1997 - Jan. 1999   Department of Biology, USTC, lecturer, Scientific Research and

                          Teaching “Molecular Genetics” & “Biochemistry”

July 1995 - Dec. 1996 Department of Biology, USTC, Assistant Professor, Scientific Research

July 1992 - Aug. 1993 Department of Biology, USTC, Teacher, Scientific Research


INTENDED AREAS OF STUDEY:

1.   The protein-based signal transduction network in response to the oxidative stress.

2.   Structural biochemistry of cyanobacterial heterocyst differentiation and toxin synthesis

3.   The proteins related to the expression, package and secretion of the silkworm fibroin.


SELECTED PUBLICATIONS

*corresponding author, #contributed equally

1.   Xu BY, Dai YN*, Zhou K, Liu YT, Sun Q, Ren YM, Chen Y, Zhou CZ*. Structure of the gas vesicle protein GvpF from the Cyanobacterium Microcystis aeruginosa. Acta Crystallographica Section D. 2014; 70(Pt 11):3013-22.

2.   Bai XH#, Chen HJ#, Jiang YL, Wen Z, Huang Y, Cheng W, Li Q, Qi L, Zhang JR*, Chen Y*, Zhou CZ*. Structure of pneumococcal peptidoglycan hydrolase LytB reveals insights into the bacterial cell wall remodeling and pathogenesis. J Biol Chem. 2014; 289(34):23403-16.

3.   Dai YN#, Zhou K#, Cao DD, Jiang YL, Meng F, Chi CB, Ren YM, Chen Y and Zhou CZ*  Crystal structures and catalytic mechanism of C-methyltransferase Coq5 provide insights into a key step of the yeast coenzyme Q synthesis pathway. Acta Crystallographica Section D. 2014; 70(Pt 8):2085-92.

4.   Shi WW#, Jiang YL#, Zhu F, Yang YH, Shao QY, Yang HB, Ren YM, Wu H*, Chen Y*, Zhou CZ*. Structure of a novel O-GlcNAc transferase GtfA reveals insights into the glycosylation of pneumococcal serine-rich repeat adhesins. Journal of Biological Chemistry. 2014; 289(30):20898-20907.

5.   Yang YH#, Jiang YL#, Zhang J, Wang L, Bai XH, Zhang SJ, Ren YM, Li N, Zhang YH, Zhang Z, Gong Q, MEi Y, Xue T, Zhang JR, Chen Y*, Zhou CZ*. Structural insights into SraP-mediated Staphylococcus aureus adhesion to host cells. PLoS Pathogens. 2014; 10(6): e1004169.

6.   Dai YN, Chi CB, Zhou K, Cheng W, Jiang YL, Ren YM, Ruan K, Chen Y, Zhou CZ*. Structure and catalytic mechanism of yeast 4-amino-4-deoxychorismate lyase. Journal of Biological Chemistry. 2013; 288(32):22985-92.

7.   Hou WT, Li WZ, Chen Y, Jiang YL*, Zhou CZ*. Structures of yeast Apa2 reveal catalytic insights into a canonical Ap4A phosphorylase of the histidine triad superfamily. Journal of Molecular Biology. 2013; 425(15):2687-98.

8.   Yu WL, Jiang YL, Pikis A, Cheng W, Bai XH, Ren YM, Thompson J, Zhou CZ*, Chen Y*. Structural insights into the substrate specificity of a 6-phospho-β-glucosidase BglA-2 from Streptococcus pneumoniae TIGR4. Journal of Biological Chemistry. 2013; 288(21):14949-58.

9.   Mu Y#, Lian FM#, Teng YB, Ao J, Jiang YL, He YX, Chen Y, Zhou CZ*, Chen X*. The N-Terminal β-Sheet of peroxiredoxin 4 in the large yellow croaker Pseudosciaena crocea Is Involved in Its Biological Functions. PLoS One. 2013; 8(2):e57061.

10. Zhang CC, Zhou CZ. ATPase as a switch in P(II) signal transduction. Proc Natl Acad Sci USA. 2013;110(32):12863-4.

11. Guo PC, Ma JD, Jiang YL, Wang SJ, Bao ZZ, Yu XJ, Chen Y, Zhou CZ*. Structure of yeast sulfhydryl oxidase Erv1 reveals electron transfer of the disulfide relay system in the mitochondrial intermembrane space. Journal of Biological Chemistry. 2012; 287(42):34961-9

12. Cheng W#, Wang L#, Jiang YL, Bai XH, Chu J, Li Q, Yu G, Liang QL, Zhou CZ* and Chen Y*. Structural insights into the substrate specificity of Streptococcus pneumoniae β(1,3) galactosidase BgaC. Journal of Biological Chemistry. 2012; 287(27):22910-8.

13. Lian FM, Yu J, Ma XX, Yu XJ, Chen Y and Zhou CZ*. Biochemical and structural insights into the catalytic cycle of the yeast peroxiredoxin Ahp1. Journal of Biological Chemistry. 2012; 287(21):17077-87.

14. He YX#, Zhang NN#, Li WF, Jia N, Chen BY, Zhou K, Zhang J, Chen Y and Zhou CZ*. N-terminal domain of Bombyx mori fibroin mediates assembly of the silk in response to the pH decrease. Journal of Molecular Biology. 2012; 418(3-4):197-207.

15. Jiang YL#, Zhang JW#, Yu WL, Cheng W, Zhang CC, Frolet C, Di Guilmi AM, Vernet T, Zhou CZ* and Chen Y*. Structural and enzymatic characterization of a Streptococcal ATP/diadenosine polyphosphate and phosphodiester hydrolase Spr1479/SapH. Journal of Biological Chemistry. 2011; 286(41):35906-14.

16. Du Y#, Shi WW#, He YX, Yang YH, Zhou CZ* and Chen Y*. Structures of the substrate-binding protein provide insights into the multiple compatible solutes binding specificities of Bacillus subtilis ABC transporter OpuC. Biochemical Journal. 2011; 436: 283-9.

17. Ma XX, Guo PC, Shi WW, Luo M, Tan XF, Chen Y and Zhou CZ*. Structural plasticity of the thioredoxin recognition site of yeast methionine-S-sulfoxide reductase Mxr1. Journal of Biological Chemistry. 2011, 286(15):13430-7.

18. Zhang X, Teng YB, Liu JP, He YX, Zhou K, Chen Y and Zhou CZ*. Structural insights into the catalytic mechanism of the yeast pyridoxal 5-phosphate synthase Snz1. Biochemical Journal. 2010; 432(3):445-50.

19. Zhao MX#, Jiang YL#, Xu BY, Chen Y, Zhang CC and Zhou CZ*. Crystal structure of cyanobacterial signal transduction protein PII in complex with PipX. Journal of Molecular Biology. 2010; 402:552-559.

20. Zhao MX, Jiang YL, He YX, Chen YF, Teng YB, Chen Y, Zhang CC* and Zhou CZ*. Structural basis for the allosteric control of the global transcription factor NtcA by the nitrogen starvation signal 2-oxoglutarate. Proc Natl Acad Sci USA. 2010; 107(28) 12487-92.

21. Luo M, Jiang YL, Ma XX, Tang YJ, He YX, Yu J, Zhang RG, Chen Y, and Zhou CZ*. Structural and biochemical characterization of yeast monothiol glutaredoxin Grx6. Journal of Molecular Biology. 2010; 398(4):614-22.

22. He YX#, Huang L#, Xue Y#, Fei X, Teng YB, Rubin-Pitel S, Zhao H* and Zhou CZ*. Crystal structure and computational analyses provide insights into the catalytic mechanism of 2, 4-diacetylphloroglucinol hydrolase PhlG from Pseudomonas fluorescens. Journal of Biological Chemistry. 2010; 285(7):4603-11.

23. Ma XX, Jiang YL, He YX, Bao R, Chen Y, Zhou CZ*. Structures of yeast glutathione-S-transferase Gtt2 reveal a new catalytic type of GST family. EMBO Reports. 2009; 10(12):1320-6.

24. Sun J, Zhang J, Wu F, Xu C, Li S, Zhao W, Wu Z, Wu J, Zhou CZ* and Shi Y*. Solution structure and metal binding properties of Kti11p from Saccharomyces cerevisiae. Biochemistry. 2005; 44: 8801-9.

25. Graille M#, Zhou CZ#, Receveur V, Collinet B, Declerck N and van Tilbeurgh H*. Activation of the LicT transcriptional antiterminator by a domain swing/lock mechanism. Journal of Biological Chemistry. 2005; 280:14780-9.

26. Zhou CZ, de la Sierra-Gallay IL, Quevillon-Cheruel S, Collinet B, Graille M, Blondeau K, Leulliot N, Sorel I, Poupon A, Janin J and van Tilbeurgh H*. Crystal structure of the yeast PX-domain protein Grd19p complexed to phosphatidylinositol-3-phosphate. Journal of Biological Chemistry. 2003; 278: 50371–6.

27. Zhou CZ, Confalonieri F*, Medina N, Esnault C, Zivanovic Y, Yang T, Jacquet M, Janin J, Duguet M, Perasso R and Li ZG. Fine organization of Bombyx mori fibroin heavy chain gene. Nucleic Acids Research. 2000; 28(12): 2413-9.